SS 2021 WS 2020
SS 2020
SS 2019 WS 2019
Department of Chemistry
open physics
KVL / Klausuren / MAP 1st HS: 13.04  2nd HS: 01.06  sem.br.: 20.07  begin WS: 17.10

2020200171 Chemical Biology (sem.br.)  VVZ 

SE weekly Christian Hackenberger, Dorothea Fiedler

Digital- & Präsenz-basierter Kurs

Aims
Praxisseminar:
Proteomic: Lysis, digestion, enrichment, pulldown, MS-Analyse
SPPS: Synthese eines zellpenetrierenden Peptids
Protein/Antibody Labeling: Fluoresence gel
Mutagenese and protein expression
Mikroskopie: Zellaufnahme
Requirements
B.Sc.
Basic knowledge in biochemistry desirable
Structure / topics / contents
1. PTMs
2. Signaling
3. Proteomik/ABPP
4. Imaging
5. Protein Folding/Proteostasis
6. Epigenetik
7. Protein Ligation
8. Biochemical Methods for unnatural protein expression (amber, auxo, metabolic eng, enzymatic)
9. Bioorthogonal/bioconjugation
10. Protein-conjugates/drug delivery
Assigned modules
WP5
Amount, credit points; Exam / major course assessment
4 SWS, 5 SP/ECTS (Arbeitsanteil im Modul für diese Lehrveranstaltung, nicht verbindlich)
For both seminars special services have to be provided. The lecture seminar will require a seminar presentation (20 min); the practical seminar will require a practical report (5-10 pages).
Other
The module will take place in the interim semester (19.08.-01.09.2019) at the FMP - Leibnizforschungsinstitut für Molekulare Pharmakologie, Robert-Rössle-Str. 10, Geb. 81, 13125 Berlin-Buch.
Contact
Prof. Hackenberger, Prof. Fiedler
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